Better Customer Care

You can place an order up to 10pm every day for next business day delivery on regular orders.

You can receive your order on weekends/holidays for an additional charge.

Faster Service

Delivery for regular orders: Next Day

Express options for regular orders:

Lower Prices

We compete on price with major oligo suppliers.

1. Scale

We provide custom DNA oligonucleotide synthesis services at 50 nmol, 200 nmol, 1.0 µmol and 10 µmol scales. Mass oligo can also be provided up to 50 mg in final product scale.

2. Purification

In addition to standard salt-free oligos (desalt), we also provide PAGE and HPLC purification at the 0.2 µmol, 1.0 µmol, and 10 µmol scales.

3. Modification

Modification services include 5’ modifications with amine, biotin, FAM, fluorescein, HEX, phosphorylation and TET. 3’ modifications include amine, biotin, fluorescein and phosphorylation. Phosphorothioation (S-oligo) and inosine modification are also possible.

We provide any of the eleven standard degenerate bases (Wobble) mixtures at any position. The standard code letters for specifying a wobble are: R=A/G, Y=C/T, M=A/C, K=G/T, S=C/G, W=A/T, B=C/G/T, D=A/G/T, H=A/C/T, V=A/C/G, and N=A/C/G/T.

4. Plate Oligo

Oligos can be provided in 96-well plate format at 50 µM/100 µM/200 µM in concentration.

The yield provided for standard oligos:

ScaleTypeTotal OD*Volume
0.05 µM Regular ≥ 4.0 200 µL
Normalization (100 µM)   100 µL
0.20 µM Regular ≥10.0 200 µL
Normalization (100 µM)   200 µL
1.0 µM Regular ≥50.0 200 µL
Normalization (100 µM)   500 µL
10.0 µM Regular ≥ 500.0  
Normalization (100 µM)   5.0 mL
* Please note that product yield in OD units may vary due to sequence and length.

The yield provided for purified oligos:

Scale Type Total OD* Volume
0.2 µM PAGE purified (Regular) ≥ 2.0 100 µL
HPLC purified (Regular) ≥ 4.0 100 µL
PAGE/HPLC
(50 µM normalization)
  50 µL
1.0 µM PAGE purified (Regular) ≥ 5.0 100 µL
HPLC purified (Regular) ≥ 10.0 100 µL
PAGE/HPLC
(50 µM normalization)
  100 µL
10.0 µM PAGE purified (Regular) ≥ 50.0  
HPLC purified (Regular) ≥ 50.0  
* Please note that product yield in OD units may vary due to sequence and length.

Normalization

Standard salt-free oligos can be normalized to a concentration of 100 µM (or 50 µM for purified oligos) without an extra charge.

Technical Specification Data Sheet

The Oligonucleotide Technical Specification Data Sheet will be shipped together with all orders and contains all the information related to the oligos we manufactured for you. The data sheet includes: Order number, oligo number, name of the oligo, sequence, length of the oligo, molecular weight, melting temperature, quantity OD, concentration in µM (nmole/µL) and ng/µl, purification and modification methods.

Packaging

Standard oligo are dissolved in TE buffer in a transparent plastic tube. Powder format and other specific buffer solutions can be provided upon request.

DNA Regular Delivery Schedule (Only Apply to San Diego Area)

DNA Regular Delivery applies to all orders with standard desalt oligos, length under 80 bases, and without any modifications or any purifications.

Daily cut-off time for a Regular Delivery order is 10pm, Sunday through Thursday.

All Regular Delivery orders received on Sunday through Thursday will be delivered between 12:30pm and 3:30pm the next business day.

All Regular Delivery orders received on Friday through Sunday will be delivered between 12:30pm and 3:30pm Monday.

All Regular Delivery orders received on a holiday will be delivered between 12:30pm and 3:30pm the next business day.

Orders with HPLC or PAGE purification will be delivered within two(2) business days after order reception.

DNA Express Delivery Schedule

Express Delivery includes:

Same Day Delivery

Orders need to be received before 10am, Monday through Friday. Delivery before 5pm the same day.


Next Morning Delivery

Orders need to be received before 3pm, Sunday through Thursday. Delivery before 10am the next business day.


Saturday/Sunday Delivery

Orders need to be received before 5pm Friday. Delivery before 1pm, Saturday or Sunday (Please specify when ordering).

Express Delivery Notes

Express Delivery service is available for San Diego area only.

Oligo length is limited to under 40 bases, desalt purification, and no modifications.

Product Format: resuspended in TE buffer.

Express Delivery Price Rate

$0.50/base for 0.05 µmole synthesis scale.

$0.80/base for 0.10 µmole synthesis scale.

$1.60/base for 0.20 µmole synthesis scale.

$3.20/base for 1.00 µmole synthesis scale.

$5.00/order delivery charge.

Better Customer Care

You can place an order up to 10pm every day for 2-4 business day delivery on single-stranded regular orders (unmodified, desalt purification) for customers in the San Diego and Los Angeles areas. All other destinations will be shipped by your carrier of choice in 2-4 business days.

Customer service representatives are available by phone M-F 8am to 10pm. If you have any urgent issues during off-hours, see our contact page for emergency contact information.

Faster Service

Delivery schedule for regular orders: 2-4 business days. See our delivery schedule for more information.

Unfortunately, our Express Delivery schedule for DNA is not available for RNA synthesis at this time. However, please feel free to contact us if your order requires special handling. Additional charges may apply.

Cheaper prices

We will gladly compete on price with major oligo suppliers, even if the synthesis scale and/or modifications are not listed on the ValueGene.com website. Please contact us for more information.

1. Scale

We provide custom RNA oligonucleotide synthesis services at the 100 nmol, 200 nmol, 1.0 µmol and 5 µmol scales. Inquire for other synthesis scales and final product yields.

2. Purification

In addition to standard salt-free oligos (desalt), we also provide PAGE and HPLC purification at the 0.1 µmol, 0.2 µmol, and 1.0 µmol scales.

3. Modification

Modification services include 5’ modifications with amine, biotin, FAM, HEX, phosphorylation and TET. 3’ modifications include amine, biotin, fluorescein and phosphorylation. Phosphorothioate (S-oligo) and inosine modification are also possible. Please contact us for other modifications as we can perform a wide variety that are not currently listed on online.

We provide any of the eleven standard degenerate bases (Wobble) mixtures at any position. The standard code letters for specifying a wobble are: R=A/G, Y=C/U, M=A/C, K=G/U, S=C/G, W=A/U, B=C/G/U, D=A/G/U, H=A/C/U, V=A/C/G, and N=A/C/G/U.

4. Plate Oligo

Oligos can be provided in 96-well plate format at no additional charge. Specify your requirements and plate positions (A1, A2,...etc.) at the time of ordering.

The yield provided for standard desalted oligos:

ScaleTypeTotal OD*Volume
0.10 µmol Regular – Desalt ≥ 4.5 Powder Format or 200 µL RNase-Free Water
0.20 µmol Regular – Desalt ≥ 10.0 Powder Format or 200 µL RNase-Free Water
1.0 µmol Regular – Desalt ≥ 40.0 Powder Format
5.0 µmol Regular – Desalt ≥ 175.0 Powder Format
* Please note that product yield in OD units may vary due to sequence and length.

The yield provided for Purified oligos:

ScaleTypeTotal OD*Volume
0.10 µmol PAGE purified ≥ 0.5 Powder Format
HPLC purified ≥ 1.0 or 100 µL RNase-Free Water
0.20 µmol PAGEpurified ≥1.5 Powder Format
HPLC purified ≥3.0 or 100 µL RNase-Free Water
1.0 µmol PAGEpurified ≥8.0 Powder Format
HPLC purified ≥15.0 Powder Format
* Please note that product yield in OD units may vary due to sequence and length.

Normalization

Normalization services are currently unavailable for RNA oligonucleotides. Please contact us if you have any special requirements.

Technical Specification Data Sheet

The Oligonucleotide Technical Specification Data Sheet is shipped together with all orders and contains all the information related to the oligos we manufactured for you. The data sheet includes: Order number, oligo number, name of the oligo, sequence, length of the oligo, molecular weight, quantity OD, concentration in µM (pmole/µL) and ng/µl, and any purification or modification methods.

Packaging

Standard RNA oligos are delivered in powder format by default in a transparent plastic tube. Solution format in RNase-free water and other specific buffer solutions can be provided upon request. Please be aware that RNA is highly susceptible to degradation, and we recommend powder format while RNA is being shipped and stored.

RNA Regular Delivery Schedule

RNA Regular Delivery applies to all orders with standard desalt oligos, length under 60 bases, and without any modifications or any purifications;

Daily cut-off time for a Regular Delivery order is 10pm, Sunday through Thursday.

All Regular Delivery orders received will be delivered between 12:30pm and 3:30pm in 2-4 business days.

Orders with HPLC or PAGE purification will be delivered within 3-5 business days after order reception.

RNA Express Delivery Schedule

Express Delivery includes:

Same Day Delivery

Orders need to be received before 10am, Monday through Friday. Delivery before 5pm the same day.


Next Morning Delivery

Orders need to be received before 3pm, Sunday through Thursday. Delivery before 10am the next business day.


Saturday/Sunday Delivery

Orders need to be received before 5pm Friday. Delivery before 1pm, Saturday or Sunday (Please specify when ordering).

Express Delivery Notes

Express Delivery service is available for San Diego area only.

Oligo length is limited to under 40 bases, desalt purification, and no modifications.

Product Format: resuspended in TE buffer.

Express Delivery Price Rate

$0.50/base for 0.05 µmole synthesis scale.

$0.80/base for 0.10 µmole synthesis scale.

$1.60/base for 0.20 µmole synthesis scale.

$3.20/base for 1.00 µmole synthesis scale.

$5.00/order delivery charge.